Anti-Mouse CD122 (IL-2Rβ) - PE

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₪1,113.60

CD122 is a 70-75 kD IL-2 receptor β chain that is a type I membrane protein.

CD122 is involved in T cell-mediated immune responses and its activation increases proliferation of CD8+ effector T cells.

It exists in three forms with varying degrees of binding affinity with IL-2.

The low affinity form is a monomer of the α subunit and has no involvement in signal transduction.

The intermediate affinity form is a γ/β heterodimer and the high affinity form is an α/β/γ heterotrimer.

The intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.

This protein also interacts with the IL-15 receptor.

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Storage and Stability

This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.

Formulation

This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

Shipping Conditions

Next Day 2-8°C